殷中琼
作者:    发布于:2011-10-20 15:28:18    点击数:9360

殷中琼老师简介

姓名

殷中琼

政治面貌

民盟

 

职称/职务

教授/药学系系主任

导师类型

硕士/博士导师

联系电话

13795840668

电子邮箱

yinzhongq@163.com

研究方向

兽医药理与毒理学,天然药物化学,新药安全性评价,新中兽药研制

学术、技术组织任职/头衔

中国畜牧兽医学会兽医药理与毒理学分会常务理事

受教育及

工作经历

1988.09—1992.07   四川农业大学  兽医公共卫生专业   学士学位

1998.09—2001.07   四川农业大学   基础兽医学        硕士学位

2001.09-2004.07    四川大学    现代遗传学与生物工程  博士学位

2004.09-2006.07    四川大学      食品安全            博士后

1992.07—1996.12  重庆市荣昌县肉联厂   质检科        副科长

1997.01-2004.09    西南大学荣昌校区   动物科技学院   副教授

2004.10—至今     四川农业大学      动物医学院  2008年晋升教授

教学课程

任职以来承担了 药物化学、药学专业专业概论,兽医病理学、兽医药理学,兽医毒理学、制药工程,天然药物的分离纯化及结构鉴定等课程的教学和科研工作。 

人才培养情况

共培养博士和硕士研究生50余名,指导校级优秀博士毕业论文2篇,省级优秀硕士论文1篇,校级优秀硕士毕业论文4篇。主要就业领域:出国深造、高校、企事业单位

科研项目

(近五年)

近五年主持和主研了各级项目20余项,目前在研的项目如下:

   1  国家自然科学基金面上项目,31372477,印楝油杀螨物质对细胞色素氧化酶表达及其蛋白特性的影响,主持人:殷中琼2014-201780万元。 

2四川省战略性新兴产品研发项目,2015GZX0010,防治仔猪细菌性腹泻疾病中药颗粒产业化开发,主研:殷中琼 , 2015-2017200万。

3 四川省科技计划项目,2015NZ0077,三类新兽药乳炎清的研究及产业化开发,主研:殷中琼,2015-201740万。

4成都市农业技术研发项目/功能性饲料添加剂川明参多糖及其硫酸酯化物的研制(2015-NY02-00266—NC主持人:殷中琼 2016-2018,经费:20万元。

5 四川省成果转化项目:宠物抗真菌药物五倍子溶液的中试生产与推广,主研:殷中琼,2016-2018,经费:50

6企业横向,三类新兽药乳炎清 “皮癣净皮螨灵的联合研究申报,主持人:殷中琼,年限2014-2018200

7企业横向, “地龙口服液、 “石苦秦粉剂、止喘宁注射液、 “止咳喘口服液三类新中兽药的非临床安全性评价及临床研究,主持人:殷中琼   经费:28万元 

主要论著、

代表性论文

以通讯作者在《Scientific Reports》,《Antivira Research》等国内外重要学术刊物上发表论文92篇,其中SCI 46篇,CSCD46篇。单篇最高影响因子5.228,累积影响因子为91.679仅附影响因子大于2SCI论文目录(按照影响因子排序): 

[1] Guangxi Wang, Zhiqiang Hu, Zhongqiong Yin*,et al.Resveratrol mitigates lipopolysaccharide-mediated acute inflammation in rats by inhibiting the TLR4/NF-κBp65/MAPKs signaling cascade. Scientific RepoRts | 7:45006 | DOI: 10.1038/srep45006(IF=5.228)

[2] Xu Song, Zhenzhen Chen, Zhongqiong Yin *, et al. Transcriptomics and proteomicstudies reveal acaricidal mechanism of octadecanoic acid-3, 4 - tetrahydrofurandiester against Sarcoptesscabieivar.cuniculi. Scientific RepoRts | 7:45479 DOI: 10.1038/srep45479 (IF=5.228)

[3] Xinghong Zhao, Jiao Xu, Zhongqiong Yin*,  et al. Antiviral effect of resveratrol in ducklings infected with virulent duck enteritis virus. Antiviral research, 2016, 130:93-100. (IF=4.909)

[4] Xu Song , Zhongqiong Yin*, Li Li,et al .Antiviral activity of sulfated Chuanminshen violaceum polysaccharide against duck enteritis virus in vitro.Antiviral Research 98 (2013) 344–351(IF=4.301) 

[5] Jiao Xu, Zhongqiong Yin*, Li Li., et al. Inhibitory Effect of Resveratrol against Duck Enteritis Virus In Vitro. PLOS ONE, 2013, 86):e65213 IF=3.730

[6] XuSong, YuetianZhang, ZhongqiongYin*, et al. Antiviral effect of sulfated Chuanmingshen violaceum polysaccharide in chickens infected with virulent Newcastle disease virus[J]. Virology, 2015, 476: 316-322. IF=3.278

[7] Xu Song, Zhongqiong Yin*, Xinghong Zhao, et al. Antiviral activity of sulfated Chuanmingshen violaceum polysaccharide against Newcastledisease virus. Journal of General Virology (2013), 94, 2164–2174 IF=3.127

[8] Guiping Yuan , Shujun Dai, Zhongqiong Yin*, et al .Toxicological assessment of combined lead and cadmium: Acute 4 and sub-chronic toxicity study in rats .Food and Chemical Toxicology, 65 (2014) 260-268  (IF=3.01)

[9] FaXiang, LianciPeng, ZhongqiongYin*, et al. Acute and subchronic toxicity as well as evaluation of safety pharmacology of Galla chinensis solution[J]. Journal of ethnopharmacology, 2015, 162: 181-190. (IF=2.939)

[10] Yong-Hua Du, Jin-Liang Li, Zhong-Qiong Yin *, et al. Acaricidal activity of four fractions and octadecanoic acid-tetrahydrofuran-3,4-diyl ester isolated from chloroform extracts of neem (Azadirachta indica) oil against Sarcoptes scabiei var. cuniculi larvae in vitro. Veterinary Parasitology, 2009, 163(7): 175–178IF=2.579

[11] Yong-Hua Du, Ren-Yong Jia, Zhong-Qiong Yin*, et al. Acaricidal activity of extracts of neem (Azadirachta indica) oil against the larvae of the rabbit mite Sarcoptes scabiei var. cuniculi in vitro[J]. Veterinary Parasitology, 2008, 157(20): 144–148IF=2.579

[12] Li L, Song X, Yin ZQ*, Jia RQ,. The antibacterial activity and action mechanism of emodin from Polygonum cuspidatum against Haemophilus parasuis in vitro. Microbiological Research, 2016 186: 139-145. (IF=2.723)

[13] Xin Lai, Qingsheng Pei, Zhongqiong Yin*, et al. The enhancement of immune function and activation of NF-κB by resveratrol-treatment in immunosuppressive mice. International immunopharmacology, 2016, 33: 42-47. (IF=2.551)

[14] Zhenzhen Chen, Yunxia Deng, Zhongqiong Yin*, et al. Studies on acaricidal action mechanism of active component from neem (Azadirachta indica) oil against Sarcoptes scabiei var. cuniculi[J]. Veterinary Parasitology, 204(2014):323-329. (IF=2.381)

[15] Zhiqiang Hu Zhenzhen Chen Zhongqiong Yin* et al. In vitro acaricidal activity of 1, 8-cineole against Sarcoptes scabiei var. cuniculi and regulating effects on enzyme activity[J]. Parasitology research, 2015 114(2015)2959-2976(IF=2.327)

[16] Jiao Xu, Qiao-Jia Fan, Zhong-Qiong Yin*, et al. The Preparation of Neem Oil Microemulsion(Azadirachta indica) and the Comparison of Acaricidal Time between Neem Oil Microemulsion and other Formulations in Vitro. Veterinary Parasitology, 169 (3-4) :399-403,2010  (IF=2.278)

[17] Xu Song#, Zhongqiong Yin* , Kuichuan Ye#, et al.. Anti-hepatoma effect of safrole from Cinnamomum longepaniculatum leaf essential oil in vitro. International Journal of Clinical and Experimental Pathology. 2014,7(5): 2265-2272 (IF=2.242)

[18] Jiao Xu, Zhi-Qiang Hu, Chuan Wang, Zhong-Qiong Yin*, et al.Acute and subchronic toxicological evaluation of 1,8-Cineole, a terpenoid oxide present in many plant essential oils, in mice.International Journal of Clinical and Experimental Pathology, 20147(4)1-7 (IF=2.242)

 [19] Hongke Lu, Guiping Yuan*, Zhongqiong Yin*, et al. Effects of subchronic exposure to lead acetate and cadmium chloride on rat’s bone: Ca and Pi contents, bone density, and histopathological evaluation. International Journal of Clinical and Experimental Pathology, 2014;7(2):640-647 (IF=2.242)

[20]Yuan GP, Dai SJ, Yin ZQ*, et al. Sub-chronic lead and cadmium co-induce apoptosis protein expression in liver and kidney of rats[J]. International journal of clinical and experimental pathology, 2014,7(6): 2905-2914. (IF=2.242)

 [21] Shujun Dai, Zhongqiong Yin*,Guiping Yuan*, et al. College Quantification of metallothionein on the liverand kidney of rats by subchronic leadand cadmium in combination. Environmental Toxicology and Pharmacology, 36(2013)  1207-1216 IF=2.005

获奖、新药、新品种等

获奖:

1主持四川省科技进步三等奖1项(2012年),排名第一;

2参与宜宾市科技进步一等奖1项(2015年),排名第二;

3 参与甘孜州科技进步三等奖1项(2011年),排名第二

新中兽药研制:

接受企业委托研制新中兽药及新中兽药安全性评价项目7项,获得新中兽药临床批件4项。新中兽药注册资料上报农业部1项。

授权专利、编著教材

申请专利20余项,目前已经授权专利12项,转让及与企业联合研发新中兽药的专利5项。

[1]殷中琼,贾仁勇,李曼,徐娇,宋旭,向发,陈振振,李莉.一种抗皮肤癣菌病的浇泼剂及其制备方法,2016,4,13,中国,专利号 ZL 2013 1 0715668.X

[2] 殷中琼,贾仁勇,代如意,徐娇,李莉,宋旭. 一种防治鸡白痢沙门氏菌病的中药制剂及其制备方法,2016,1,20,中国,专利申请号:ZL 2013 1 0715602.0

[3] 殷中琼,贾仁勇,徐娇,宋旭, 李莉,蔡红.一种防治鸭疫里默氏杆菌病的中药制剂及其制备方法,2015,8,19,中国,专利申请号:ZL 2013 1 0715698.0

[4] 魏琴,殷中琼,杜永华,贾仁勇,范静,周黎军,徐州. 一种油樟挥发油水乳剂,2015,11,25,中国,专利申请号:ZL 2013 10324142.9

[5] 殷中琼,贾仁勇,程安春,宋旭,徐娇.具有免疫增强活性和抗病毒功效的植物多糖硫酸酯化物的制备方法及应用,201501,中国,专利申请号:ZL.2012 1 0191422.0

[6] 殷中琼,贾仁勇,李曼,李莉. 一种治疗皮肤癣菌病的中药复方涂膜剂及其制备方法,2014,12.05,中国,申请专利号:ZL 201310121790.4

[7] 殷中琼,贾仁勇,舒杨,李忠梁,赵建,舒刚,吕程,梁晓霞。一种防治草原鼠害的植物源抗生育剂及其制备方法和应用,20141022,中国,申请专利号:ZL 2013 1 0188586.4

[8]殷中琼,李福杏,贾仁勇,王亮,宋旭. 一种防治大肠杆菌病的中药制剂及其制备方法与应用,2013.12,中国,专利申请号:ZL 201210191430.7

[9] 殷中琼, 魏琴,贾仁勇,周黎军,杜永华,杨华兴,蒋勤久. 一种油樟叶挥发油包合物及其制备方法,2013.01,中国,专利申请号:( ZL 2011102776780

[10] 殷中琼,李金良,贾仁勇. 印楝油中酯类化合物及其制备方法和应用,2011.11,中国,专利申请号:ZL 200810044697.7

[11] 殷中琼,贾仁勇. 具有降血脂和保健功能的中药胶囊的制备方法及其用途,2011.09,中国,专利申请号:ZL2009100587274

[12] 殷中琼,郭文竹,贾仁勇.一种防治奶牛乳房炎的黄连提取物溶液剂及其制备方法,2017.02,中国,专利申请号:ZL201410845171.4  

 

社会服务

长期围绕畜禽疾病和鼠害开展生物防治技术研究,研制了防治畜禽疾病的抗病营养型中兽药和控制草原鼠害的植物源不育剂等生物防治产品10余个。社会服务领域主要:畜禽养殖场、甘孜州和阿坝州等草原,对于畜禽疾病的防治、减少抗生素残留、保障食品安全和草原鼠害生物防治等问题产生了重大影响

 

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