导师类型

硕导

办公地点

6-309

职称/职务

副教授

电子邮箱

luoqihui@sicau.edu.cn

研究方向

动物微生物与免疫学、实验动物学

学术、技术组织任职/头衔

中国动物微生态学会，常务理事

中国畜牧兽医学会高级会员

中国实验动物学会，会员

四川省海外高层次留学回国人才

教育背景及工作经历

2002年，西南大学，获学士学位；

2005年，西北农林科技大学，获硕士学位；

2012年，四川农业大学，获博士学位；

2005年至今，四川农业大学，任教

2013年，四川农业大学，副教授

2018年，美国Iowa State University，访问学者

教学课程

基因工程、实验动物学、动物检疫技术

人才培养情况

培养毕业硕士研究生12名，在读硕士生4名

科研项目

（近五年）

1.四川省科技厅,鸭源鹅细小病毒对樱桃谷肉鸭肠道菌群结构及黏膜屏障功能的影响，2019年；

2.四川省留学人员优先资助科技项目，动物冠状病毒流行病学分析，2021年；

3.四川省国际科技创新合作项目：基于MPTP诱导帕金森猕猴模型探究氯碘羟喹药效及其作用机制，2020年；

4.国家重大科学仪器设备开发专项：MSFRI在视网膜疾病猕猴繁育与动物模型评价中的应用，2018年

主要论著、

代表性论文

[1]QihuiLuo,XinyuLei,JingXu,AsadJahangir,JunboHe,ChaoHuang,WentaoLiu,AnchunCheng,LiTang,YiGeng,ZhengliChen.   An altered gut microbiota in duck-origin parvovirus infection on cherry   valley ducklings is associated with mucosal barrier.Poultry Science, 2021,100(4):101021.

[2] Qihui Luo, Chengjie Lao, Chao Huang, Yu   Xia, Wenjing Ma, Wentao Liu, Zhengli Chen. Iron Overload Resulting from the   Chronic Oral Administration of Ferric Citrate Impairs Intestinal Immune and   Barrier in Mice. Biological Trace Element Research, 2021, 199:1027–1036.

[3] Qihui Luo, Jing Xu, Chao Huang, Xinyu   Lei, Dongjing Cheng,Anchun Cheng，Zhengli Chen,et al. Impacts of Duck-Origin Parvovirus Infection on   Cherry Valley Ducklings From the Perspective of Gut Microbiota. Front   Microbiol[J]. 2019 Mar 28;10:624. doi: 10.3389/fmicb.2019.00624.

[4] Qihui Luo, Yifan Li, Chao Huang,   Dongjing Cheng, Wenjing Ma, Yu Xia, Wentao Liu and Zhengli Chen. Soy Isoflavones Improve the Spermatogenic Defects in   Diet-Induced Obesity Rats through Nrf2/HO-1 Pathway. Molecules,2019,24:2966

[5] Liangqin Shi, Chao Huang, Qihui Luo, Yu   Xia, Wentao Liu, Wen Zeng, Anchun Cheng, Riyi Shi, Chen Zhengli. Clioquinol   improves motor and non-motor deficits in MPTP-induced monkey model of   Parkinson’s   disease through AKT mTOR pathway. Aging-US, 2020,12(10):9515-9533.

[6] Jinlong Tan, Chao Huang, Qihui Luo,   Wentao Liu, Dongjing Cheng, Yifan Li, Yu Xia, Chao Li, Li Tang, Jing Fang,   Kangcheng Pan, Yangping Ou, Anchun Cheng and Zhengli Chen. Soy Isoflavones   Ameliorate Fatty Acid Metabolism of Visceral Adipose Tissue by Increasing the   AMPK Activity in Male Rats with Diet-Induced Obesity (DIO).   Molecules,2019,24:2809

[7] Liangqin Shi, Chao Huang, Qihui Luo,   Edmond Rogers, Yu Xia, Wentao Liu, Wenjing Ma,Wen Zeng, Li Gong, Jing Fang,   Li Tang, Anchun Cheng, Riyi Shi, Zheng-li Chen.The association of iron and   the pathologies of Parkinson’s diseases in MPTP/MPP+-induced neuronal degeneration in non-human   primates and in cell culture. Frontiers in Aging Neuroscience,2019,11:215.

[8] Chao Huang, Wenjing Ma, Qihui Luo,   Liangqin Shi, Yu Xia, Chengjie Lao, Wentao Liu, Yuanfeng Zou, Anchun Cheng,   Riyi Shi, Zhengli Chen. Iron overload resulting from the chronic oral   administration of ferric citrate induces parkinsonism phenotypes in middle-aged   mice. Aging-US,2019,11.

[9] Jingfei Chen, Qihui Luo, Chao Huang,   Wen Zeng, Ping Chen, Qi Gao, Bing Chen, Wentao Liu, Lingzhen Pan, and Zhengli   Chen.Morphology of Inner Retina in Rhesus Monkeys of Various Ages: A   Comparative Study.Journal of Ophthalmology,2019,7,

[10]Chao Huang, Wenjing Ma, Qihui Luo,   Liangqin Shi, Yu Xia, Chengjie Lao, Wentao Liu, Yuanfeng Zou, Anchun Cheng,   Riyi Shi, Zhengli Chen. Iron overload resulting from the chronic oral   administration of ferric citrate induces parkinsonism phenotypes in middle-aged   mice. Aging-US,2019,11.

[11]Jinlong Tan, Chao Huang, Qihui Luo,   Wentao Liu, Dongjing Cheng, Yifan Li, Yu Xia, Chao Li, Li Tang, Jing Fang,   Kangcheng Pan, Yangping Ou, Anchun Cheng and Zhengli Chen. Soy Isoflavones   Ameliorate Fatty Acid Metabolism of Visceral Adipose Tissue by Increasing the   AMPK Activity in Male Rats withDiet-Induced Obesity (DIO).   Molecules,2019,24:2809

[12] Luo Q, Chen B, Xu J, Ma W, Lao C, Li   Y, Tan J, Tang Y, Huang C, Liu W, Chen Z. Development of a SYBR Green II   Real-Time Polymerase Chain Reaction for the Clinical Detection of the   Duck-Origin Goose Parvovirus in China. Intervirology[J]. 2018;61(5):230-236.

[13] Qihui Luo, Dandan Yang, Qi Qi, Chao   Huang, Bing Chen, Wentao Liu, Liangqin Shi, Yu Xia, Li Tang, Jing Fang,   Yangping Ou, Yi Geng, and Zhengli Chen. Role of the Death Receptor and   Endoplasmic Reticulum Stress Signaling Pathways in Polyphyllin I-Regulated   Apoptosis of Human Hepatocellular Carcinoma HepG2 Cells. BioMed Research   International,2018,https://doi.org/10.1155/2018/5241941.

[14] Qihui Luo, Shanshan Chen, Juan Deng,   Liangqin Shi, Chao Huang, Anchun Cheng, Wentao Liu, Jing Fang, Li Tang, Yi   Geng, Zhengli Chen.Endocannabinoid hydrolase and cannabinoid receptor 1 are   involved in the regulation of hypothalamus-pituitary-adrenal axis in type 2   diabetes. Metabolic Brain Disease,2018,33:1483–1492

[15]Chao Huang, Chengcheng Yang, Dejiang   Pang, Chao Li, Huan Gong, Xiyue Cao, Xia He, Xueyao Chen, Bin Mu, Yiyuan Cui   , Wentao Liu, Qihui Luo, Anchun Cheng, Lanlan Jia, Mina Chen , Bo Xiao and Zhengli Chen.Animal models of   male subfertility targeted on LanCL1-regulated spermatogenic redox   homeostasis. Lab Animal, 2022, 51, 1-13.

[16]Chao Huang, Huan Gong, Bin Mu, Xinting   Lan, Chengcheng Yang, Jinlong Tan, Wentao Liu, Yuanfeng Zou, Lixia Li, Bin   Feng, Xia He, Qihui Luo and Zhengli Chen.BAF-L Modulates Histone-to-Protamine   Transition during Spermiogenesis." International Journal of Molecular   Sciences, 2022, 23, 1985

[17]熊昕宜，许泽玉,何念佳,何俊博,陈正礼,黄超,刘文涛,罗启慧.大豆异黄酮干预肥胖大鼠肝氧化应激及炎症反应,浙江农业学报, 2022, 34( 5) :942-948

[18]陈兵,徐婧,罗启慧,黄超,刘文涛,吴洪,陈镜妃,陈苹,高琪,马文静,陈正礼.感染鸭源小鹅瘟病毒QH-L01株樱桃谷雏鸭病理学研究.浙江农业学报, 2018, 30( 6) :932-938

[19]高爽,谭金龙,罗启慧,黄超,刘文涛,陈正礼.大豆异黄酮对油酸致大鼠肝损伤的干预作用.中国细胞生物学学报, 2020, 42(5): 829–838.

[20]唐伊,谭金龙,罗启慧,黄超,刘文涛,陈正礼.大豆异黄酮对大鼠骨骼肌纤维组织形态及肌收缩蛋白表达的影响.中国细胞生物学学报, 2018, 40(8): 1319–1325.

[21]陈苹,李立科,陈晓林,李一帆,罗启慧,黄超,刘文涛,陈正礼.大豆异黄酮对大鼠肝脏脂肪酸代谢的影响.四川农业大学学报,2018,36(2):267-272.

[22]陈苹,罗启慧,黄超,李立科,李一帆,陈晓林,刘文涛,陈正礼.大豆异黄酮对健康大鼠肝脏DGAT1、CB1R、FAAH表达的影响.西北农林科技大学报（自然科学版）,2018,46(5).

[23]夏玉,罗启慧,祝春梅,陈正礼.大豆异黄酮对去卵巢大白鼠垂体雌激素受体和白细胞介素–2表达的影响.湖南农业大学学报(自然科学版) 2018, 44(1):82–87.

创新实验、科研兴趣计划项目（近五年，注立项时间）

1、国家级大学生创新性项目，恒河猴NT-proBNP快速检测方法的建立，2018；

2、科研兴趣项目，大豆异黄酮对食源性肥胖大鼠肝脏氧化应激和炎症反应的影响，2021；

3、科研兴趣项目，鸭CD3ε和CD8α多克隆抗体的制备和应用，2020；

授权专利、编著教材

1.罗启慧.马文静.劳澄婕.陈正礼,黄超,刘文涛,夏玉. 一种慢性食源性帕金森病小鼠模型及其建立方法和应用, 2019-10-21,中国, CN201911002647.7.

2罗启慧,史良琴,陈正礼,刘衡,李立科,黄超,刘文涛,方静,唐丽,曾文,龚立.灵长类帕金森病模型行为学评价优化方法.公开（公告）号：CN105878240A）.

3.罗启慧,史良琴,陈正礼,曾文,黄超,龚立,李立科,刘衡,刘文涛,方静,唐丽. 一种慢性进程性帕金森病恒河猴模型的建立.公开（公告）号：CN105662638A). 4.罗启慧,陈正礼,黄丹凤,程安春,黄超,彭西,方静,唐丽,曾文,龚立. 恒河猴免疫抑制模型的建立.发明专利公开（公告）号­: CN105030794A.

5.罗启慧,陈正礼,曾文,程安春,龚立,毕凤君,曾立才. 一种诱导糖尿病模型的建立方法.发明专利（授权号：Z201310275715.3）.

社会服务

提供实验动物质量检测及评价、模型评价及各种动物微生物检测等